Scientist. Builder. Systems thinker.

Microbiology and immunology background. Practical software, tools, and systems.

I bring research discipline to software, automation, and applied AI. My focus is on creating practical, durable, and useful systems that leverage complex systems thinking carried over from the world of biology.

Ben Ralph, PhD

About

My background is rooted in rigorous scientific inquiry. I earned my B.Sc. Honours, M.Sc., and Ph.D. in Microbiology and Immunology at McGill University. My doctoral work focused on manipulating the innate and adaptive immune responses to develop novel therapeutic approaches for Aspergillus fumigatus pulmonary infections. That work included basic and vaccine-based research into host defense, airway infection, and how immune pathways could be directed toward better protection.

As my career progressed, I moved into translational molecular biology and antibody-based work across both academic and industry settings. Today, I also apply that same analytical discipline to practical software, tools, and systems, while immunology, host-pathogen interactions, and molecular biology remain core parts of my background and interests.

Education Ph.D. Microbiology & Immunology, McGill
Ph.D. Focus Innate and adaptive immune responses to Aspergillus fumigatus pulmonary infection
Research Areas Immunology, host-pathogen interactions, molecular biology
Translational Work Antibody-based research, molecular biology, academic-industry collaboration

Work

Listmize

A product focused on structured capture and decision workflows, emphasizing cleaner inputs and useful organization.

Time Tracker

A self-hosted Flask time tracker built for real project work, including billable work, internal work, personal projects, and backfilled time entry without locking data into a SaaS.

MeterScan Wizard

A utility for scanning and analyzing power or gas meter signals using RTL-SDR and rtlamr, with summaries and heatmaps to optimize logging conditions.

Trick or Treater Counter

A Flask web application for tracking Halloween visitors, visualizing counts with charts, and exporting results for year-over-year comparison.

Research

Timeline

  • 2007 – 2018 McGill University B.Sc. Hons, M.Sc., Ph.D. Student
  • 2019 RI-MUHC Postdoctoral Fellow
  • 2020 – 2025 IRIC (Institute for Research in Immunology and Cancer) Postdoctoral Fellow & Research Assistant
  • 2020 – 2025 MediMabs Postdoctoral Fellow

Publications

View on PubMed
  1. The IL-1 Receptor Is Required to Maintain Neutrophil Viability and Function During Aspergillus fumigatus Airway Infection. Frontiers in Immunology, 2021
  2. A Murine Model for Chronic A. fumigatus Airway Infections. Methods in Molecular Biology, 2021
  3. Galectin-3 enhances neutrophil motility and extravasation into the airways during Aspergillus fumigatus infection. PLoS Pathogens, 2020
  4. Contribution of IL-1RI Signaling to Protection against Cryptococcus neoformans 52D in a Mouse Model of Infection. Frontiers in Immunology, 2017
  5. Aspergillus fumigatus CalA binds to integrin alpha(5)beta(1) and mediates host cell invasion. Nature Microbiology, 2016
  6. Posaconazole-Loaded Leukocytes as a Novel Treatment Strategy Targeting Invasive Pulmonary Aspergillosis. Journal of Infectious Diseases, 2017
  7. Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation. mBio, 2016
  8. Eyelid Mycetoma Masquerading as Sebaceous Carcinoma. Ophthalmic Plastic and Reconstructive Surgery, 2017
  9. The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps. PLoS Pathogens, 2015
  10. Evolution of the Immune Response to Chronic Airway Colonization with Aspergillus fumigatus Hyphae. Infection and Immunity, 2015
  11. Impact of Leishmania mexicana infection on dendritic cell signaling and functions. PLoS Neglected Tropical Diseases, 2014
  12. Host cell signalling and leishmania mechanisms of evasion. Journal of Tropical Medicine, 2012
  13. Identification of key cytosolic kinases containing evolutionarily conserved kinase tyrosine-based inhibitory motifs (KTIMs). Developmental and Comparative Immunology, 2010

Now

Since March 2025, I have been focused on full-time parenting. This chapter has sharpened my perspective on what deserves attention and what does not.

Currently, I am exploring small, focused products, privacy-aware tooling, practical AI, and systems that remain understandable and maintainable long-term.

Connect

I tend to be interested in a wide mix of things, from science and immunology to development, automation, systems, and practical ideas worth building. If you think there may be common ground, LinkedIn is the best place to get in touch.

Connect on LinkedIn